Cannabis -vs- Hyptertension

​​​​​​cannabis  We conclude that endocannabinoids tonically suppress cardiac contractility in hypertension and that enhancing the CB1-mediated cardiodepressor and vasodilator effects of endogenous anandamide by blocking its hydrolysis can normalize blood pressure. Targeting the endocannabinoid system offers novel therapeutic strategies in the treatment of hypertension.  In animals, CBD reduced infarct size and reduced inflammation follow a heart attack.  Cannabidiol, a nonpsychoactive cannabis constituent, protects against myocardial ischemic reperfusion injury.  CBD reduced acute and apoptotic brain damage when administered shortly after an ischemic brain event in mice.  The neuroprotective effect of cannabidiol in an in vitro model of newborn hypoxic-ischemic brain damage in mice is mediated by CB(2) and adenosine receptors. Cannabinoids administered to humans shortly after a stroke reduced infarct volume and improved brain functional outcome. Cannabinoids in experimental stroke: a systematic review and meta-analysis.